How you prepare

To prepare for your prostate biopsy, your urologist may have you:

• Provide a urine sample to analyze for a urinary tract infection. If you have a urinary tract infection, your prostate biopsy will likely be postponed while you take antibiotics to clear the infection.
• Stop taking medication that can increase the risk of bleeding — such as warfarin (Jantoven), aspirin, ibuprofen (Advil, Motrin IB, others) and certain herbal supplements — for several days before the procedure.
• Do a cleansing enema at home before your biopsy appointment.
• Take antibiotics before your prostate biopsy to help prevent infection from the procedure.